GLIFAZ
Tablet
Dose Type
Information
(GLIFAZ) Empagliflozin is a sodium glucose co-transporter-2 (SGLT-2) inhibitor indicated as an adjunct to diet and exercise to improve glycemic control in adult patients with type 2 diabetes. SGLT2 co-transporters are responsible for reabsorption of glucose from the glomerular filtrate in the kidney. The glucuretic effect resulting from SGLT2 inhibition reduces renal absorption and lowers the renal threshold for glucose, therefore resulting in increased glucose excretion. Additionally, it contributes to reduced hyperglycaemia and also assists weight loss and blood pressure reduction.
Therapeutic Class
Anti-Diabetic, SGLT2 inhibitor
Dose and Direction of Use
Take this tablet by mouth with or without food as prescribed by your doctor. The dosage provided is based upon your medical condition and repsonse to the treatment. Take this medicatin regularly for the better result.
Mode of Action
Empagliflozin works by inhibiting the sodium-glucose co-transporter-2 (SGLT2) found in the proximal tubules in the kidneys. Through SGLT2 inhibition, empagliflozin reduces renal reabsorption of glucose and increases urinary excretion of glucose. The glucose-lowering effect of the drug is independent of insulin.
Uses
Type 2 Diabetes Mellitus
Contraindications
Don't use this medicine if you have:
- Hypersensitivity to the Active Substance or to any of the Excipients.
- Severe renal impairment (eGFR <30 ml/min/1.73 m2)
Precautions and Warning
- Talk to your doctor or patient if you have medical condition as such liver problem, kidney problem, high cholestrol or heart problem.
- Make sure to limit alcohol intake with this medication as it can lead to low blood sugar level and high ketone level
- Low blood pressure can cause dizziness or blurred vision. So, limit any driving or machinery work that requires attention. You can pack a biscuit or chocolate with you for low blood pressure.
- Consult to your doctor about your eating habits and maintain a proper Diabetes Plate Method.
- Make sure you follow light exercise in your day to day lifestyle.
- Follow doctor's advice if you are pregenant or planning for one. You should not take this medication if you are in the second or third trimester of pregnancy.
- This medication is not suitable for Type 1 Diabetic patient and for the treatment of diabetic ketoacidosis.
- Doctor should monitor the sign and symptoms of ketoacidosis which is nausea, vomiting, stomach pain, confusion and trouble in breathing.
- Don't double the dose for the missed dose.
